The present study was aimed to investigate the effect of selected plants on haematological parameters of DMBA induced
breast cancer of albino rats. Sixty-three female albino rats were used for the study and they were grouped into nine
groups of seven animals each. Group I (control) was fed with normal feed. Groups II to IX, were orally administered 20mg
DMBA/kg to induce tumour. Group II was untreated; Group III was treated with tamoxifen(6.6mg/kg). Groups IV- IX were
treated with 500mg/kg Sorghum vulgare, 1000mg/kg Sorghum vulgare, 500mg/kg Eremomastax polysperma; 1000mg/kg
Eremomastax polysperma, 500mg/kg Brillantaisia owariensis and 1000mg/kg Brillantaisia owariensis respectively.
Treatment with the different aqueous concentrate demonstrated significant increase (p≤ 0.05) of haemoglobin, and
packed cell volume levels of the treated groups when compared to the DMBA group. There was a decrease in Neutrophil,
N/L, P/L and platelets level in the treated groups when compared to the DMBA group (though not significant, p≤ 0.05).
The present study reveals that the plants might be able to reduce anaemia posed as a result of breast cancer.
